| Personalized bacteriophage therapy for difficult-to-treat infections | June 20, 2024 | Jonathan Iredell, Holly Sinclair, Ameneh Khatami | Nature microbiology vol. 9,6 (2024): 1401-1402. doi:10.1038/s41564-024-01712-y | Phage therapy, personalised phage, perspective | | |
| Comparison of clinical characteristics and outcomes of patients with sepsis identified by the Sepsis-3 criteria by blood and urine culture results: A multicentre retrospective cohort study | June 19, 2024 | Ling Li, Jannah Baker, Aldo Saavedra, Carl Suster, Michelle Moscova, Jonathan Iredell, Amith Shetty | Health science reports vol. 7,6 e2162. 19 Jun. 2024, doi:10.1002/hsr2.2162 | Blood culture; critical care outcomes; hospital mortality; pathology; sepsis; urine | | |
| Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study | June 4, 2024 | Jean-Paul Pirnay, Sarah Djebara, Griet Steurs, Johann Griselain et al. | Nature microbiology vol. 9,6 (2024): 1434-1453. doi:10.1038/s41564-024-01705-x | Phage therapy, case studies, Belgian consortium, phage immune neutralisation | | |
| Phage Therapy in Korea: A Prescribers' Survey of Attitudes Amongst Korean Infectious Diseases Specialists Towards Phage Therapy | December 1, 2023 | Shinwon Lee, Stephanie A Lynch, Ruby CY Lin, Heejoon Myung, Jonathan R Iredell | Infection & chemotherapy vol. 56,1 (2024): 57-65. doi:10.3947/ic.2023.0067 | Survey, phage therapy, Korean Infectious Diseases Clinicians | | |
| Mammalian cells internalize bacteriophages and use them as a resource to enhance cellular growth and survival | October 26, 2023 | Marion C. Bichet, Jack Adderley, Laura Avellaneda-Franco, Isabelle Magnin-Bougma, Natasha Torriero-Smith, Linden J. Gearing, Celine Deffrasnes, Cassandra David, Genevieve Pepin, Michael P. Gantier, Ruby CY Lin, Ruzeen Patwa, Gregory W. Moseley, Christian Doerig, Jeremy J. Barr | PLoS biology vol. 21,10 e3002341. 26 Oct. 2023, doi:10.1371/journal.pbio.3002341 | Bacteriophages, cellular responses, phagocytosis, AKT pathways, Infalmmatory response | | |
| Quantifying the Economic and Clinical Value of Reducing Antimicrobial Resistance in Gram-negative Pathogens Causing Hospital-Acquired Infections in Australia | June 23, 2023 | Gordon JP, Al Taie A, Miller RL, Dennis JW, Blaskovich MAT, Iredell JR, Turnidge JD, Coombs GW, Grolman DC, Youssef J. | Infect Dis Ther. 2023 Jul;12(7):1875-1889. doi: 10.1007/s40121-023-00835-9. Epub 2023 Jun 21. PMID: 37341866; PMCID: PMC10390426. | Antimicrobial resistance, public health, Australia, sepsis, health economics model | | |
| Quantifying the Economic and Clinical Value of Reducing Antimicrobial Resistance in Gram-negative Pathogens Causing Hospital-Acquired Infections in Australia | June 21, 2023 | Jason P. Gordon, Amer Al Taie, Ryan L. Miller, James W. Dennis, Mark A. T. Blaskovich, Jonathan R. Iredell, John D. Turnidge, Geoffrey W. Coombs, David Charles Grolman & Jacqueline Youssef | Infectious Diseases and Therapy 12, 1875–1889 (2023). https://doi.org/10.1007/s40121-023-00835-9 | Phage Therapy, Polyclonal Bacteraemia, Staphylococcus aureus | | |
| Pharmacokinetics/pharmacodynamics of phage therapy: a major hurdle to clinical translation | February 2, 2023 | Sue C Nang, Yu-Wei Lin, Aleksandra Petrovic Fabijan, Rachel YK Chang, Gauri G Rao, Jonathan Iredell, Hak-Kim Chan, Jian Li | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases vol. 29,6 (2023): 702-709. doi:10.1016/j.cmi.2023.01.021 | Antimicrobial; Bacteriophage; Pharmacodynamics; Pharmacokinetics; Self-replication | | |
| Phage Therapy of Mycobacterium Infections: Compassionate-use of Phages in Twenty Patients with Drug-Resistant Mycobacterial Disease | January, 2023 | Rebekah M. Dedrick, Bailey E. Smith, Madison Cristinziano, Krista G. Freeman, Deborah Jacobs-Sera, Yvonne Belessis, A. Whitney Brown, Keira A. Cohen, Rebecca M. Davidson, David van Duin, Andrew Gainey, Cristina Berastegui Garcia, C.R. Robert George, Ghady Haidar, Winnie Ip, Jonathan Iredell, Ameneh Khatami, Jessica S. Little, Kirsi Malmivaara, Brendan J. McMullan, David E. Michalik, Andrea Moscatelli, Jerry A. Nick, Maria G. Tupayachi Ortiz, Hari M. Polenakovik, Paul D. Robinson, Mikael Skurnik, Daniel A. Solomon, James Soothill, Helen Spencer, Peter Wark, Austen Worth, Robert T. Schooley, Constance A. Benson, Graham F. Hatfull | Clinical Infectious Diseases vol. 76,1 (2023): 103-112. doi:10.1093/cid/ciac453 | mycobacteriophage; nontuberculous mycobacteria; phage therapy. | | |
| Standardised treatment and monitoring protocol to assess safety and tolerability of bacteriophage therapy for adult and paediatric patients (STAMP study): protocol for an open-label, single-arm trial | December 9, 2022 | Ameneh Khatami, David A Foley, Morgyn S Warner, Elizabeth H Barnes, Anton Y Peleg, Jian Li, Stephen Stick, Nettie Burke, Ruby C Y Lin, Julia Warning, Thomas L Snelling, Steven Y C Tong, Jonathan Iredell and Phage Australia Clinical Network | BMJ Open vol. 12,12 e065401. 9 Dec. 2022, doi:10.1136/bmjopen-2022-065401 | general medicine (see internal medicine); infectious diseases; microbiology; paediatrics; therapeutics | | |
| Development and validation of a miniaturized bacteriophage host range screening assay against antibiotic resistant Pseudomonas aeruginosa | October, 2021 | Renee Nicole Ng, Lucinda Jane Grey, Andrew Vaitekenas, Samantha Abagail McLean, Jack Dylan Rudruma, Daniel Rodolfo Laucirica, Matthew Wee-Peng Poh, Jessica Hillas, Scott Glenn Winslow, Joshua James Iszatt, Thomas Iosifidis, Anna Sze Tai, Patricia Agudelo-Romero, Barbara Jane Chang, Stephen Michael Stick, Anthony Kicic. | Journal of Microbiological Methods vol. 190 (2021): 106346. doi:10.1016/j.mimet.2021.106346 | Bacteriophages; Host range; Miniaturization; Phage therapy; Pseudomonas aeruginosa | | |
| How I manage a patient with MRSA bacteraemia | October, 2021 | Joshua S. Davis, Neta Petersiel, Steven YC. Tong | Clinical Microbiology & Infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases vol. 28,2 (2022): 190-194. doi:10.1016/j.cmi.2021.10.014 | Antibiotics; Bacteraemia; Methicillin-resistant Staphylococcus aureus; Therapeutic drug monitoring; Vancomycin | | |
| Phage therapy in pediatrics: the way forward for difficult-to-treat infections? | October, 2021 | Annaleise R. Howard-Jones, Jonathan R. Iredell & Ameneh Khatami | Expert review of anti-infective therapy vol. 20,4 (2022): 487-491. doi:10.1080/14787210.2022.1990755 | Bacteriophage; biofilm; multi-drug resistant organisms; pediatrics; therapeutic monitoring | | |
| Antibiotic resistance in uropathogens across northern Australia 2007–20 and impact on treatment guidelines | September, 2021 | Will Cuningham, Shalinie Perera, Sonali Coulter, Graeme R Nimmo, Trent Yarwood, Steven Y C Tong, Teresa M Wozniak | JAC-antimicrobial resistance vol. 3,3 dlab127. 14 Aug. 2021, doi:10.1093/jacamr/dlab127 | Antibiotic resistance, Uropathogens, Escherichia coli, Klebsiella pneumoniae, surveillance | | |
| Phage Therapy for Multi-Drug Resistant Respiratory Tract Infections | September, 2021 | Joshua J. Iszatt, Alexander N. Larcombe, Hak-Kim Chan, Stephen M. Stick, Luke W. Garratt and Anthony Kicic. | Viruses vol. 13,9 1809. 11 Sep. 2021, doi:10.3390/v13091809 | Bacteriophage; infectious disease; multi-drug resistance; respiratory | | |
| How Many Health Research Biobanks Are There? | September, 2021 | Sheila O'Donoghue, Simon Dee, Jennifer A. Byrne, and Peter Hamilton Watson | Biopreservation and biobanking vol. 20,3 (2022): 224-228. doi:10.1089/bio.2021.0063 | Biobank; locators; numbers | | |
| Bacterial lysis, autophagy and innate immune responses during adjunctive phage therapy in a child | August, 2021 | Ameneh Khatami, Ruby C Y Lin, Aleksandra Petrovic-Fabijan, Sivan Alkalay-Oren, Sulaiman Almuzam, Philip N Britton, Michael J Brownstein, Quang Dao, Joe Fackler, Ronen Hazan, Bri’Anna Horne, Ran Nir-Paz, Jonathan R Iredell | EMBO molecular medicine vol. 13,9 (2021): e13936. doi:10.15252/emmm.202113936 | Pseudomonas aeruginosa; bacteriophage; child; immune response; osteoarticular infection | | |
| Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage | August, 2021 | Rhys A. Dunstan, Rebecca S. Bamert, Matthew J. Belousoff, Francesca L. Short, Christopher K. Barlow, Derek J. Pickard, Jonathan J. Wilksch, Ralf B. Schittenhelm, Richard A. Strugnell, Gordon Dougan, and Trevor Lithgow | Microbiology spectrum vol. 9,1 (2021): e0102321. doi:10.1128/Spectrum.01023-21 | Klebsiella; bacteriophages; capsular polysaccharide; cryo-EM; depolymerase | | |
| Bacteriophage adaptation to a mammalian mucosa reveals a trans-domain evolutionary axis | May, 2021 | Wai Hoe Chin, Ciaren Kett, Oren Cooper, Deike Müseler, Yaqi Zhang, Rebecca Bamert, Ruzeen Patwa, Laura C. Woods, Citsabehsan Devendran, Joe Tiralongo, Trevor Lithgow, Mike J. McDonald, Adrian Neild, Jeremy J. Barr | bioRxiv | pre-print, doi: https://doi.org/10.1101/2021.05.11.443681 | Bacteriophages, co-evolution, gut mucosa, genetic recombination, mucin glycans | | |
| Component Parts of Bacteriophage Virions Accurately Defined by a Machine-Learning Approach Built on Evolutionary Features | May, 2021 | Tze Y. Thung, Murray E. White, Wei Dai, Jonathan J. Wilksch, Rebecca S. Bamert, Andrea Rocker, Christopher J. Stubenrauch, Daniel Williams, Cheng Huang, Ralf Schittelhelm, Jeremy J. Barr, Eleanor Jameson, Sheena McGowan, Yanju Zhang, Jiawei Wang, Rhys A. Dunstan, and Trevor Lithgow | mSystems vol. 6,3 (2021): e0024221. doi:10.1128/mSystems.00242-21 | Klebsiella; antimicrobial resistance; artificial intelligence; bacteriophage; bacteriophage therapy; bacteriophages; machine learning; phage therapy; virion structure | | |
| Annals for Hospitalists Inpatient Notes - Clinical Pearls—Methicillin-Resistant Staphylococcus aureus Bacteremia | May, 2021 | Steven Y.C. Tong | Annals of internal medicine vol. 174,5 (2021): HO2-HO3. doi:10.7326/M21-1491 | Staphylococcus, MRSA, Clinical | | |
| Phage Biobank: Present Challenges and Future Perspectives | February, 2021 | Ruby CY Lin, Jessica C Sacher, Pieter-Jan Ceyssens, Jan Zheng, Ali Khalid, Jonathan R Iredell, The Australian Phage Biobanking Network. | Current opinion in biotechnology vol. 68 (2021): 221-230. doi:10.1016/j.copbio.2020.12.018 | Phage biobank, data sovereign, management system, sustainability | | |
| A Phage Therapy Guide for Clinicians and Basic Scientists: Background and Highlighting Applications for Developing Countries | February, 2021 | Ali Khalid, Ruby C. Y. Lin and Jonathan R. Iredell | Frontiers in microbiology vol. 11 599906. 11 Feb. 2021, doi:10.3389/fmicb.2020.599906 | antibiotic resistance; bacteriophage; developing countries; disease burden; mortality | | |
| Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials | January, 2021 | Fernando Gordillo Altamirano, John H. Forsyth, Ruzeen Patwa, Xenia Kostoulias, Michael Trim, Dinesh Subedi, Stuart K. Archer, Faye C. Morris, Cody Oliveira, Luisa Kielty, Denis Korneev, Moira K. O’Bryan, Trevor J. Lithgow, Anton Y. Peleg & Jeremy J. Barr | Nature microbiology vol. 6,2 (2021): 157-161. doi:10.1038/s41564-020-00830-7 | Acinetobacter, Phage-resistance, Research paper | | |
| Rapid automated system for bacteriophage virulence and antibiotic synergy testing – The ‘phago-antibiogram’ | December, 2020 | Ali Khalid, Aleksandra Petrovic Fabijan, Susan Maddocks, Ruby CY Lin, Jonathan R Iredell | International Journal of Infectious Diseases Volume 101, 134 | Phage Virulence, Antibiotic synergy, Research paper | | |
| The Promise of viral phage therapy in hernia mesh infection, is this the biological ‘silver bullet’ of the future? | November, 2020 | Peter Speck, Morgyn Warner, Jason Clark, Anita Jacombs, Alex Karatassas, Chris Hensman | ANZ journal of surgery vol. 90,11 (2020): 2161-2164. doi:10.1111/ans.16214 | Phage therapy, hernia mesh infection | | |
| Improving Academic Biobank Value and Sustainability Through an Outputs Focus | August, 2020 | Amanda Rush, Daniel R. Catchpoole, Rod Ling, Andrew Searles, Peter H. Watson, Jennifer A. Byrne | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research vol. 23,8 (2020): 1072-1078. doi:10.1016/j.jval.2020.05.010 | Policy Perspective, Phage biobank, sustainability | | |
| Efficacy of phage cocktail AB-SA01 therapy in diabetic mouse wound infections caused by multidrug-resistant Staphylococcus aureus | July, 2020 | Legesse Garedew Kifelew, Morgyn S. Warner, Sandra Morales, Lewis Vaughan, Richard Woodman, Robert Fitridge, James G. Mitchell & Peter Speck | BMC microbiology vol. 20,1 204. 9 Jul. 2020, doi:10.1186/s12866-020-01891-8 | Diabetic mice; Infection; MDR S. aureus; Phage cocktail; Treatment; Wound | | |
| Isolating and characterising phages against Pseudomonas aeruginosa and Staphylococcus aureus in children with cystic fibrosis | June, 2020 | Jagdev Singh, Dinesh Subedi, Fernando Lautaro Gordillo Altamirano, Ruzeen Patwa, Hiran Selvadurai, Jeremy Barr, Ameneh Khatami | Journal of Cystic Fibrosis | Cystic Fibrosis, Phage isolation, Pseudomonas, Staphylococcus, Pediatrics | | |
| Efficacy of Lytic Phage Cocktails on Staphylococcus aureus and Pseudomonas aeruginosa in Mixed-Species Planktonic Cultures and Biofilms | May, 2020 | Legesse Garedew Kifelew, Morgyn S. Warner, Sandra Morales, Nicky Thomas, David L. Gordon, James G. Mitchell, and Peter G. Speck. | Viruses vol. 12,5 559. 18 May. 2020, doi:10.3390/v12050559 | Pseudomonas aeruginosa; Staphylococcus aureus; biofilm; efficacy; fluorescence; mixed-species culture; phage cocktail therapy; planktonic culture | | |
| Phage therapy for severe bacterial infections: a narrative review | April, 2020 | Aleksandra Petrovic Fabijan, Ali Khalid, Susan Maddocks, Josephine Ho, Timothy Gilbey, Indy Sandaradura, Ruby CY Lin, Nouri Ben Zakour, Carola Venturini, Bethany Bowring, Jonathan R Iredell | The Medical journal of Australia vol. 212,6 (2020): 279-285. doi:10.5694/mja2.50355 | Bacteroa; omfectopms; infection control, bacteriophage | | |
| Isolation and Characterization of Klebsiella Phages for Phage Therapy | March, 2020 | Eleanor M. Townsend, Lucy Kelly, Lucy Gannon, George Muscatt, Rhys Dunstan, Slawomir Michniewski, Hari Sapkota, Saija J. Kiljunen, Anna Kolsi, Mikael Skurnik, Trevor Lithgow, Andrew D. Millard, and Eleanor Jameson | PHAGE (New Rochelle, N.Y.) vol. 2,1 (2021): 26-42. doi:10.1089/phage.2020.0046 | Klebsiella; antibiotics; antimicrobial resistance; bacteriophage; characterization; nosocomial infection; phage; phage therapy; virulence | | |
| Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia A Randomized Clinical Trial | February, 2020 | Steven Y C Tong, David C Lye, Dafna Yahav et al and Australasian Society for Infectious Diseases Clinical Research Network | JAMA vol. 323,6 (2020): 527-537. doi:10.1001/jama.2020.0103 | ClinicalTrials.gov Identifier: NCT02365493; Randomised controlled trial; MRSA bacteremia | | |
| Safety of bacteriophage therapy in severe Staphylococcus aureus infection | 2020 | Aleksandra Petrovic Fabijan, Ruby CY Lin, Josephine Ho, Susan Maddocks, Nouri L. Ben Zakour, and Jonathan R. Iredell. | Nature microbiology vol. 5,3 (2020): 465-472. doi:10.1038/s41564-019-0634-z | Phage therapy, Australia, therapeutic monitoring, single-arm non-comparative trial, sepsis, infective endocarditis | | |
| Bacteriophage Therapy of Ventilator-associated Pneumonia and Empyema Caused by Pseudomonas aeruginosa | November 1, 2019 | Susan Maddocks, Aleksandra Petrovic Fabijan, Josephine Ho, Ruby CY Lin, Nouri L Ben Zakour, Chris Dugan, IvanaKliman, Steven Branston, Sandra Morales, JOnathan R Iredell | American journal of respiratory and critical care medicine vol. 200,9 (2019): 1179-1181. doi:10.1164/rccm.201904-0839LE | case study, phage therapy, AmpliPhi phage cocktail | | |
| Polyclonal Staphylococcus aureus Bacteremia | September 17, 2019 | Aleksandra Petrovic Fabijan, Nouri L Ben Zakour, Josephine Ho, Ruby CY Lin, Jonathan R Iredell, Westmead Bacteriophage Therapy Team and AmpliPhi Biosciences Corporation | Annals of internal medicine vol. 171,12 (2019): 940-941. doi:10.7326/L19-0369 | case reports, polyclonal Staphylococcus aureus bacteremia, phage therapy | | |
